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Innovations in HIV Therapy
ISSUE: SEPTEMBER, 2007 Despite recent advances in HIV/AIDS
therapy, issues such as universal
drug availability, drug costs, and
treatment infrastructure, as well as several
important clinical issues, remain of significant
concern.
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AIDS Wasting Syndrome In the 21st Century
ISSUE: SEPTEMBER, 2007 Historically, wasting syndrome has
been described in association with
opportunistic infections and/or AIDSrelated
malignancies.1 In 1987, the Centers for
Disease Control and Prevention defined
wasting syndrome as involuntary weight loss
(of >10% from baseline) accompanied by
chronic diarrhea, documented fever for more
than 30 days, and asthenia.
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HIV and Herpesvirus Infections
ISSUE: SEPTEMBER, 2007 As opportunistic infections, the
human Herpesviridae play a
significant role in the
morbidity and mortality of individuals
with HIV disease.
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NEW! Combination Therapy in the Treatment of HIV—An Update
ISSUE: APRIL, 2007 Over the past 10 years, an impressive armamentarium of combination antiretrovirals (ARVs) has been developed, significantly improving the options available to manage HIV/AIDS. In all, 4 fixed-dose combinations (FDCs) and a 3-drug combination of tenofovir disoproxil fumarate, emtricitabine, and efavirenz—the first FDC, formed through the collaboration of multiple pharmaceutical industry partners, to achieve triple-drug combination ARV therapy in a single pill per day—have thus far received FDA approval.
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Treatment Options For HIV
ISSUE: SEPTEMBER, 2006 Over the past year, the field of infectious
diseases has marked both the
25th anniversary of the first reported
cases of AIDS and the 10th
anniversary of the beginning of the
widespread use of potent combination antiretroviral
therapy.
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HIV and Herpesvirus Infections
ISSUE: SEPTEMBER, 2006 As opportunistic infections, the human Herpesviridae play a significant role in the morbidity and mortality of individuals with human to provide an updated reference on these diseases with recomimmunodeficiency virus (HIV) disease.
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Commentary: The End of the Epidemic?
ISSUE: SEPTEMBER, 2006 HIV infection cannot be cured, and the virus
is still being transmitted. However, the
AIDS epidemic may already have ended.
What can that possibly mean?
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HIV and Herpesvirus Infections
ISSUE: SEPTEMBER, 2005 As opportunistic infections, the human Herpesviridae play a significant
role in the morbidity and mortality of individuals with HIV. The
Herpesviridae are ubiquitous DNA viruses; with the exception of herpes
simplex virus-2 (HSV-2) and human herpesvirus-8 (HHV-8), the
Herpesviridae are highly prevalent in the general population.
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